# Research

## Our research philosophy

Pelago is dedicated to delivering safe and effective care for our members. In order to do so we turn to science, conducting research and peer-reviewed studies. Substance use disorders can be treated in a variety of ways, including social support, therapy, medication or a combination of treatments. But what is the most effective? Through rigorous research, we validate and refine our treatment approaches, leveraging outcomes of scientific inquiry to guide custom solutions for each individual who participates in our programs.

We’ve found some interesting results so far and we encourage you to take a look at the data yourself.

### 52%

biochemically-verified quit rate at 28 days

### 44%

biochemically verified quit rate at 26 weeks post-quit date

### 71%

more likely to remain abstinent from tobacco at 12 months

## Economic Impact of an Employer-Sponsored Integrated Digital Intervention Targeting Substance Use Disorders

#### $6,758

Average medical cost savings per participants over 12 months

#### 4.5:1

Return on investment in 12 months (including Pelago program fee)

#### 33%

Lower medical spend driven by fewer inpatient, outpatient, and ER claims

## Feasibility and acceptability of a novel digital therapeutic combining behavioral and pharmacological treatment for opioid use disorder

## Number of Abstinent Days (past 30)

- 0 Days
- 1-10 Days
- 11-20 Days
- 21-29 Days
- 30 Days

#### 67%

abstinent over 90 days

#### 95%

average medication adherence

overall decrease in depression & anxiety

overall increase in well-being

## Implementing Suicide Risk Screening in a Virtual Addiction Clinic

#### 252

Screened patients

#### 7.5%

Screen-positive rate

#### 100%

of clinicians were comfortable asking patients about suicidal thoughts and behaviors

## Feasibility and Preliminary Outcomes of a Mobile Intervention Combining Cognitive Behavioral Therapy, Virtual Coaching, and Nicotine Replacement Therapy for Nicotine Vaping Cessation

#### 87%

of participants quit vaping

time vaping decreased from 75.8 minutes to 26.5 minutes

days vaping decreased from 24.7 to 3.9

## Feasibility, Acceptability, and Preliminary Outcomes of an Integrated Telemedicine Intervention Combining Naltrexone and Cognitive Behavioral Therapy for Alcohol Use Disorder

## Changes in mean percentage of days abstinent

#### 68%

of participants reduced their alcohol use

drinks per day decreased from 6.7 to 2.7

#### 96%

participation and satisfaction